Ok so hello all and thanks to any replies. Definitely looking for opinions or experiences from other people with the similar set up. Basically, I am looking to start learning to shoot a handgun and am stuck with the fun curse of being right handed but left eye dominant. Now the only handgun experience I have is shooting off rounds for fun as a kid, wasting ammo with a M9 in the military, attempting to shoot at javelina pigs in Arizona, and then most recently actually going to a range with a bunch of co-workers to shoot at targets with a variety of calibers and handguns/revolvers (basically wanted an idea of what I liked the feel of before going to shop). I spent about half the time shooting with my right hand/right eye, other right hand/left eye, and the difference with the 22 off the bat was huge. Left eye was great grouping and near where I was trying to hit, right eye was just all over the place. With a 357, 44 or 45 not much difference but I was also just tossing rounds down the range (was there mostly to get a feel for what felt good in my hand, and had so many shooting same targets was hard to find my shots). Now I know no-matter what I do I need to just get a 22 that I feel comfortable holding, a ton a rounds, and lots of days on the range. I'm debating forcing myself to get better right hand/right eye, go ahead and shoot left eye/right hand which seemed to work best, or since I'm just learning a pistol go left hand/left eye (which I didn't think to try at the time). My concern is, is there any way this might effect my shooting with a rifle if I learn to shoot differently? I shoot right handed/right eye, and the only time it ever really gets annoying is if I am shooting with my left eye closed for an hour or two straight. I initially tried left hand/left eye with a rifle, and though my grouping was always good i could never get comfortable and keep my position consistent (I'd throw quarter size groups all over the place). When I did finally decide to go right/right I spent the next 6 years of my military life shooting expert or hawk-eye every time I picked up a rifle. Shooting for fun or hunting was just as easy. If I decide to go left handed/left eye with a pistol, I am wondering if this will mess me up with my rifle shooting. I guess the other option would be to split my shooting time between pistol and rifle at the range, but that is a whole other chunk of change I would have to consider spending.