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Small game with a .22. Other than that nothing. Calibers that are meant for man stopping have no business in the deer woods unless in the hands of a competent marksman and super experienced hunter. Then the only reason to do it is for the challange.
 

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I've hunted deer with my .45 ACP quite a bit. You really need to know what you're doing and be able to get up close to take a shot.
 

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best thing to hunt with a semi auto pistol is people.
also small varmints drop pretty well from a pistol
a 22 with shotshells will end a snake real well as well
 
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