Here's the situation. I have a home defense handgun (XDm-9mm-Compact) which I will also use as a CCW when I get the permit. I keep it loaded and chambered with Hornady Critical Defense 115 gr rounds. Let's say I go to the range once a week to practice and clean my weapon after each session. When I go to the range (and again when I break it down for cleaning) I unload my self defense rounds including the one in the chamber. In the most extreme case, I could put the same round back in the chamber over 100 times per year. I realize that it would not be difficult to alternate the top two rounds, reducing the cycles to about 50 per year. In fact, I could rotate each round in a 19+1 magazine so each would cycle only about 5 times (kind of a pain in the a$$). I realize that I also have the option to go ahead and fire the one chambered round as the first round of practice and slowly consume my self defense ammo. The question is: How many times can a factory loaded, self defense round be chambered before the condition of the round is compromised? I am wondering about both the plastic plug in the hollowpoint and the bullet in the casing. I'm sure there are plenty of opinions out there, does any one know of study work done on this issue?