I have a weakness for N Frame S&Ws. For a shooter you will probably never wear out, look into a model 28. If pretty matters, look at the model 27 (basically the same gun with a higher polished finish).
Since you apparently have no objection to used revolvers, I would suggest you take a look at the various Colt Trooper models. A lot of quality and prices are not all that bad if you look around. FWIW, the original Colt Trooper is called "the poor man's Python" because it used the same frame & internals. Later versions are quite good, but the design changed, getting away from the expensive to produce older design.
Dan Wessons are still going for decent money if you can find what you like. Not as nicely styled as Colt & S&W (IMHO), but I don't think you can hurt them with any loads that could be considered responsible. They have also earned a reputation for excellent accuracy.
As for used Rugers, keep an eye out for a Security Six. Excellent revolvers with all of the Ruger durability. Rumor has it that they were discontinued because they were getting to be too expensive to produce for their price range. I personally think they are better looking than their modern replacements, opinions vary of course.