As said, talk to the ATF.
However, I do business with several 01 FFLs that have their operations at their home (one is a danged good gunsmith).
You must be legal (zoning, business license) you must have a designated premises (cannot operate ONLY at gun shows)
You must have established operating hours (could be 1-4 on Saturdays)
You MUST intend to "engage in the business" of buying and selling guns. If you use it only for personal buying, will not fly.
And. as said, talk to the ATF.