i was thinking about this, and i was like "yeah, i guess the mini might suck for a lefty..." when it just dawned on me that my nephew, who is a southpaw, never had any trouble at all with my mini. i didn't really think about it to be honest, even while we were shooting (other than he had to go to a lefty bench at the range).
and this isn't a knock, but i think the AR could possibly be a problem cause of all the blowback into the chamber (in your face). just thinking out loud there. but the AR charging handle (though i still don't like it) is far more ambidextrous than the mini.