I used to be a night sight convert but then someone much greater than I explained it this way to me.
If you're using night sights (tritium), and running a flashlight on the weapon, or in home defense, plan to use a flashlight to illuminate the target, then the night sights appear black, against the beam.
If you're using a flashlight, then get a fiber optic front sight which will grab that ambient light and illuminate with a flashlight much better than a night sight will.
He actually recommended a fiber optic front sight, with blacked out rear sights, for quicker target acquisition in low to dark lighting. It's quicker since you're going off the front sight dot and not lining up a 3 dot front and rear setup, which isn't really necessary for home defense and self defense distances...
"If you remember nothing else about what I’m about to consider here, remember this: the one and only reason politicians, bureaucrats, and policemen want to take your weapons away from you is so that they can do things to you that they couldn’t do if you still had your weapons."— L. Neil Smith