IMO, a comp on a .45 ACP is like putting a rear spoiler on a front drive car.
The key to a comp is the speed of the bullet pasing through. The smaller calibers produce enough to make the comp very effective.
"A well regulated Militia, being necessary to the security of a free State, the right of the people to keep and bear Arms, shall not be infringed."
Life Member NRA
Life Member NAHC
Former President of the ECPT (Eifel Combat Pistol Team)