Unless you have SPECIFIC listing showing that a particular gun/barrel will handle +P+ ammo, DO NOT USE IT WITHOUT CONFIRMATION!!
SAAMI pressure specs for +P+ are pretty high...as in, about as high as the handloads that cause KABOOMS in Glocks and other pistols.
Had a guy kaboom a S&W SIGMA at the range a couple years ago with +P+, its downright dangerous to use in guns not rated for it...
you like having fingers, right?