Doubt you'll have a problem, it's a fine gun. My Gen 2 G22 has been great.
Some people have complained that putting a light on the rail can cause feeding problems with some magazines. A stiffer mag spring usually takes care of the problem.
The biggest issue with assembling an AR isn't so much getting the parts together right - it's getting the right parts together.
US Army 1966-69, VFW Life Member, Retired Geek