Some bullets just don't shoot worth a hoot out of some guns.No matter how many powders,primers,length changes that are tried,they just don't work.
There are so many small things that can cause this,and it will drive you nuts if you let it.Just try a different type of Nosler bullet,if that's what you want to shoot.
I'm kind of anal with my loads,if they don't shoot around .50 moa,I'll only try them a few times with changing things and then go to something different.Some guy's are happy if they shoot MOA,but I've been doing this a long time and have too many loads that will shoot around .25 moa to waste time trying out one particular bullet that doesn't do what I want.
Texas State Rifle Association
North American Hunting Club