I run 748 in my .308, with great results. But, Im only runnin 42g behind a 150 Nosler Ballistic Tip. Very accurate in 4 different .308s so far, none have shot them over .5". Mine will cloverleaf 125s, 150s, 165s, and 168s. Never tried any heavier. Most of the time Im using the 150g NBT with 748, or SST with 4895.