Where do you live...I mean, an apartment, house, duplex, mobile home?
Are there others in close proximity, behind walls in nearby rooms, nearby dwellings, busy neighborhood?
This should be a big consideration for you as traditionally, a FMJ projectile has a tendency for overpenetration...IE...exiting an assailant or missing altogether and still being dangerous to those who are unknowingly in the path.
The JHP's upon expansion cause a larger wound channel, (bigger hole, more loss of blood, quicker drop in BP, quicker end to threat) and IMHO are not as apt to over penetrate.
Ask yourself these questions and use your best judgement...