I have used SxSs from 20 gauges thru 10 gauges for decades with no problems. I do not like O/Us at all. Nothing wrong with either gun type, just personal preference. An O/U does have to break open quite a bit more to clear the bottom barrel, and that can be a pain in a tight blind.
I have gone back to repeaters because I don't shoot anything as much as I used to, and switching gun types doesn't help your shooting average in any event.
Depending on your personal fire control practices, you may find you miss the third shot at times. But, if you want to shoot a SxS go ahead and enjoy. Old Nash did okay with one.