I've had excellent results with my Mossberg 500, the factory Xfull choke and Winchester 2oz 3" #4s.
27 one shot kills in a row.
Here's a quote from a study by the Oklahoma Department of Wildlife Conservation:
the 3-inch Winchester Double X Magnum Turkey load with 2 ounces of No. 4 lead shot exceeded both pattern density parameters, and it registered the highest pattern percentage (94%) of all lead loads tested at 40 yards!
These loads are not just "adequate" or "acceptable" out to 40 yards, they are downright deadly
. If you want to shoot farther than that, it's time to pony up for heavier than lead loads.