It's not legal
in most (if not every) State in the USA to use rimfires for deer.
That's not to say it hasn't been done...jacklighters have been using 'em for nighttime illicit hunting since they came out.
On the other hand, if the Anti-gunners get their way, we will be stuck with Rimfire Only
just like the UK...and our critters are WAY BIGGER than anything you will find in England.
And try to do-in a Feral Hog with a .22WMR...well, let's say you better make a VERY precise shot.
Forget dealing with Bear or Wolves with a .22WMR...they're just gonna stick the gun up yer wazoo.
Granted a little old lady used a .22lr on a bear, and got a once-in-a-lifetime-shot off and dropped the big bruin.
But I'd hate to bet my life on a rimfire. Even one with 30-round mags like the Keltec PMR-30,
or the Grendel P-30, P-31, R-31's...I'd use 'em as backups, but for a primary I've got a 10mm