Originally Posted by redscho
In 1887 the Stevens Arms Co. developed the ultimate in .22 rimfire cartridges, the .22 Long Rifle. This used the .22 Long case with a 40 grain RN bullet loaded to higher velocity than the 29 grain Long bullet. It shot flatter and hit harder than any of the previous .22 rimfires except the .22 Extra Long, whose performance it essentially duplicated in a shorter case, and it was more accurate than that cartridge.
The .22 Long Rifle caught on, was adapted to both rifles and pistols, and became the most popular sporting and target shooting cartridge in the world. After the advent of smokeless powder a High Velocity version of the .22 LR was introduced, which further extended the .22 LR's superiority as a small game hunting cartridge.
...thats all well and good but... it's still a "revolver" cartridge. Well suited to "revolvers" and long guns which employ either fixed tubular magazine or detachable "rotary" magazines.
Marketing is great and all but I've personally fired an example of every stick mag feed semi auto .22 LR "pistol" and "rifle" available... and EVERY SINGLE ONE OF THEM JAMMED EXCESSIVELY.
The only .22 LR guns I've fired with a "reasonable" malfunction rate are Rugers 10-22 carbine, Single Six Revolver, and an uncles Henry Golden Boy.
This has also been my experience with other "revolver" cartridges chambered in stick feed semi autos such as:
Desert Eagle .44 Mag... JAMOMATIC... suspect .357 Mag would be as bad.
However... I've fired Desert Eagle .50 AE and an AMT .50 AE which were both reliable. The difference being that the .50 AE does not have the "cylinder lip" at the base of it's casing like the .22LR, .357, .44, Ect, Ect.
With enough time, effort, and expense, and care in loading, is it possible to "make" a stick fed .22 LR "reliable?" Yes... people do it every day... but that does not change the fact that the casing design, when used in stick fed semi autos, IS inherently LESS reliable than pistol cartridges that were actually designing for stick fed semi auto use.
Nothing wrong with the .22 LR but the OP did ask what to "stay away" from. Rather than just telling him to go with the 10-22, Golden Boy, or Single Six, I thought it might be good to tell him why.