I have never messed around with supressers, but my understanding has been that supressers are less effective with revolvers than autos, due to the cylinder gap.
If I were to try to supress a .22 auto, I would choose a Ruger Mk I, II, or III. My first gun was a Mk I, and I have usually had one in my collection. A great little gun.
I'm not sure how they would work with suppressers, but a great .22 target revolver is the old K-22 (later Smith model 17). Not made anymore and a little pricey, but very accurate. I have one made about 1957. Another revolver suggestion is the Ruger Single Six Convertible, which (with interchangeable cylinders) can handle .22 lr or .22 mag.