No Sir~ Dimensional differences in the upper and lower receivers. In the case of the 15-22 it also has a polymer receiver not aluminum. But S&W changed dimensions to prevent that from happening as far as I know!
The Constitution is not an instrument for the Government to restrain the people. It is an instrument for the people to restrain the Government!
America will never be destroyed from the outside. If we falter and lose our freedoms, it will be because we destroyed ourselves.
As far as I know it takes a true 5.56 with a 22lr conversion to do what you are asking. Not the 22LR's as the majority of them are custom machined for the 22LR. Find a smitty/machinist to test your theory. I'm betting a lot of modifications will be required.