22 lr is a different cartridge from a 22 WRF (Winchester rimfire) or the 22 WRM (Winchester Rimfire Magnum) WRF and WRM are a larger diameter cartridge case and a larger diameter bullet. So called "mini-mags" or "maxi-mags" are a brand name- they are still 22 LR. The WRF is sort of a "22 Mag Short" and CAN be fired from a 22 Mag. 22 LR cannot- the case will split, and the bullet sorta wobbles down the barrel. 22 WMR will not chamber in a 22 LR firearm.
Now, if THAT did not confuse ya- there are a few.22 Revolvers that have 2 different cylinders- and by swapping cylinders, can shoot either one. Have a Colt Peacemaker Single Action like that. But those are the only ones hat swap. Capish?