ive got a lot of 22lr firearms and spend a LOT of time shooting them but they arent good for defensive purposes. if its all i got i would use it, but its just not a good idea.
if your thinking about shtf you might consider a suppressed 22lr pistol very very very quiet game getter. less noise signature than most crossbows.
"Gun control: The theory that a woman found dead in an alley, raped and strangled with her panty hose, is somehow morally superior to a woman explaining to police how her attacker got that fatal bullet wound." — L. Neil Smith
The problem with being stupid is you cannot simply decide to stop doing dumb things...
"I crapped my pants to avoid the draft!!" -Ted Nugent