I can tell you from experience don't ever try to mix a 45 offset rail mount to a rail mounted site. Either use two 45's or two rails at 1:30. It's likely if you mix you won't be able to zero
Learned the hard way hehe. I was able to zero, but the front sight post was almost entirely unscrewed and wobbly.... Moved the rear sight from my 45 to another two inch rail on my hand guard at 45/1:30 and it was almost a natural factory zero at neutral on the sites.