I noticed how new you were when you used "clip" to mean "magazine".
Ammunition will definitely have an affect on handgun performance, point of impact, and reliability.
Some firearms a very ammunition sensitive
"A well regulated Militia, being necessary to the security of a free State, the right of the people to keep and bear Arms, shall not be infringed."
Life Member NRA
Life Member NAHC
Former President of the ECPT (Eifel Combat Pistol Team)