I've taken numerous deer, elk, and a few moose with my .30-06. I use 150 grain bullets for everything.
IME, there is no need for anything more powerful in the lower 48.
"Eargeschplitten loudenboomers" are for Africa.
Place the bullet from a .30-06 properly, and it will do the job.
I didn't fight to defend your freedom so you could vote to take away mine.
"A man who has nothing for which he is willing to fight, nothing which is more important than his own personal safety, is a miserable creature and has no chance of being free unless made and kept so by the exertions of better men than himself.
John Stuart Mill."