I've taken numerous deer, elk, and a few moose with my .30-06. I use 150 grain bullets for everything.
IME, there is no need for anything more powerful in the lower 48.
"Eargeschplitten loudenboomers" are for Africa.
Place the bullet from a .30-06 properly, and it will do the job.
I didn't fight to defend your freedom so you could vote to take away mine.