Originally Posted by JonM
You would need to rezero anyway. If you change bullets even a 150 for a different 150 you need to rezero before hunting.
Not always true, barrel harmonics can give you the same POI with different weight/speed bullets at a given range. My 30-06 impact the same point with both 150gr TTSXs at 3040fps and 165gr BTSP at 2920fps, but if I go to 180gr harmonics is working aginst me and I am WAY off (7" low at 100 yards!) the moons of Juipter don't usualy align like that though, best to pick a load capable of the largest game you hunt and stick with it.