If I was only going to hunt varmints! It would be the 22-250 over the 25-06 would be my choice! Or the 243 Winchester would be a better choice over the 25-06 for varmints. However, if you had future plans are to deer hunt or similar game in the future then my choice would be the 25-06 for starters! The reason for the previous comments would be based on availability and cost of the ammunition. And of course the selection of the game you are hunting.
The Constitution is not an instrument for the Government to restrain the people. It is an instrument for the people to restrain the Government!
“Americans have the right and advantage of being armed. Unlike the people of other countries, whose leaders are afraid to trust them with arms.”
James Madison. Author of the 2nd Amendment