I don't know about a 22 short but during trapping season we usually live pretty good during trapping season between my brother in law with his 22 rifle and me with my 22 pistol we usually don't go hungry.
But for everything else 300 win mag you can kiss targets at long range or just blow them in have up close.
"come on you sons of b***hs! do you want to live forever?" Sergeant Daniel Daly, USMC, Belleau Wood France June 6th 1918
"You can be as mad as a mad dog at the way things went. You could swear, curse the fates, but when it comes to the end, you have to let go" Benjamin Button