I really like the 2022 myself, but I guess it depends on caliber. If you're new to shooting, the 2022 in 9mm is a solid choice. The pistol itself is not terribly expensive, is of good quality, and has a good reputation for quality.
The P220 has a great reputation for reliability and accuracy but I don't recommend the .45 for a first gun. I think if you were going to go with a .45 the SIG is probably one of the better choices.
There is also the P227 coming soon which is the 220 but with a larger magazine capacity. Honestly though, maybe not worth waiting for as it is just a 10 rounder.
Of course, 9mm and .45 are both difficult to find right now. The 2022 is available in .40 S&W, but like .45 not something I generally encourage for a brand new shooter. However, .40 S&W is still on the shelves, but in limited quantities as well.