If carry is not a factor, I'd take a P226 over a P229 every time. You get the advantages of higher capacity, longer barrel (better ballistics), and longer sight radius (easier to be accurate with). I'd also recommend checking out the P227 (similar gun, but in 45acp).
Many of us prefer 45acp to 40sw. The 40sw is a fine defense caliber that absolutely will take care of business. But 45acp tends to lend itself to being faster and more accurate with...in regard to succession, at least.
Almost any alloy-framed Sig that falls within the numerical model range of P210-245 is going to be a fantastic but expensive gun. It's simply about finding the one that best suits your hands and your needs.