I've shot 226 and 229. I went with the p229 based on ergonomics. It fit my medium sized hand like a glove. My p229 is an E2 mode so it has the ergo grip and really suited my grip perfectly and it has the SRT and SIGlite night sights.
As a range gun it's great, for HD it's railed so you can add a light or laser if you want, and the p229 is available in 9, 40 and .357 s&w. plus they even make a .22 kit for it as well. As a CC it really depends on the holster and clothing as it is rather on the larger end of the compact spectrum of pistols and tends to print a bit. But you'd have the same issue if not worse with the p226.
I must have put at least 700 rounds thru her and not one FTE or FTF or any other glitch whatsoever. Love it.
SIG 1911 .45 ACP
SIG P229R 9mm
Beretta BU9 Nano 9mm
Beretta 84FS .380 ACP
Ruger MKIII 22/45 Target .22LR
PWS (Primary Weapons Systems) MK114 5.56