I asked Talon the same question, here is their response.
"I was giving your e-mail regarding your holster. These are designed to be carried anywhere from about 2 o'clock to around 4, maybe 5 o'clock in the waistband. I personally carry the Shield, same holster as yours basically, at about 4. If you have trouble reaching way around to the small of your back, I would suggest moving it slightly forward. I would not recommend carrying the left handed holster so you can draw with the back of your hand against the body. We always recommend the palm of the hand be facing the body when drawing. Otherwise, you will point the gun at yourself when presenting the pistol. Under stress, this can cause you to unintentionally shoot yourself.
We design the holster with a straight up draw, with no real cant built in. The tuckable may have a little more cant if you want to try that one."
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