Welcome to the forum, personally I'm not a big fan of the ankle rig unless it's a backup option. Going to the ankle for your primary option in a self defense situation would be weird for me but YMMV. I carry a Kel-tec in an ankle rig as a backup option to my winter EDC. Definitely check out the M&P compact line as they do have the thumb safety option you are looking for.
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"Regardless of whether justified of not, you will feel sad about killing another human being. It is better to be sad than to be room temperature." - Joe B Fricks.
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01 FFL, GOFFA, NRA, GOA, IAVA, VFW, ABATE of Iowa D15.
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