Location: I see you, and you will not know when I will strike
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Lasers point TWO ways. They also don't help much in bright light or direct sunlight.
I vote no, and I had a set of Crimson Trace on my carry pistol for years. Having been exposed to their glaring downside by someone much more knowledgable than I, chose to take them off my Sig and put them in the safe.
My 1911's have good, healthy grips and night sights.