I am 6' 276 lbs 45 ACP 10+1 Taurus PT145, US ARMY, disabled Vietnam Vet.
I carry right side, (Right handed). Get some tightie whities. If you are a 52 waist, get 48's and so on.
Get a pocket holster, the kind with the no slip strap like the one I have, the BlackHawk size 4 works for my .32, .38, 9mm, and 45. In Florida the heat goes up the caliber goes down!
Go to your favorite seller of defense stuff and they should let you try it out with your carry choices. Walk around the place and move like you do. Oh, and it does help a bit to use those shirts with the square bottoms outside the pants. And then never ever forget to remove it in the bathroom stalls at Denny's!