I have a friend that carries one in 45 Colt/.410 Shotgun. I think he only uses 45 Colt with his though. I am not impressed with the accuracy of the .410 out of a pistol. I have only seen videos. But they have all shown a huge spread at like 10 yards. Big enough to be shooting innocents off to the side or behind. The 45 Colt on the other hand is a formidable round for self defense.
I personally do not carry anything with less than 5 rounds in it.
Romans 1:16 I am not ashamed of the gospel, because it is the power of God for the salvation of everyone who believes: first for the Jew, then for the Gentile.