The Ranger SXT is as good as any. I keep my .45 loaded with them. My bedside gun (41mag) is loaded with Gold Dots. If you're worried about overpenetration with the shotgun I'd suggest loading the 1st 2 rounds with 2 3/4" #4 turkey magnums and the rest with #1 buck or #4 buck. The most important thing by far is to make SURE what's behind your target when you shoot. This has to be instilled in through training and more training. In an actual defense situation your training will take precedence through instinct over thinking because all thought processes will go out the window. Massive amounts of adrenaline dumping into your system is the culprit of that. Practicing drills will help immensely toward instinctive action and your aiming/shooting.
Sometimes you earthlings REALLY amaze me!