A big bore revolver is always a good choice when it comes to shooting things

! The dang ammo costs might put a smack down on your wallet though

. The ammo cost for 44 Special, 44 Magnum, and 45 Colt are so close together that you can't rule one in or out without doing the same to the other two. I kind of lean towards the 45 Colt
Ruger® Redhawk® Double-Action Revolver Model 5027
You can easily go from mild cowboys loads to wild dracula dropers without doing any reloading. The cowboy loads would be easy enough to enjoy shooting all day, and then you could load up Gold Dots, Glasers, or whatever floats your boat. If you wanted to go with a real heavy hitter,
Grizzly Ammunition 45 Colt (Long Colt) +P 260 Grain Bonded Core Jacketed Flat Point Box of 20 - MidwayUSA
Grizzly has loads as heavy as 335 grains. I don't think you could go wrong with either caliber. You would be more right with the 45 Colt

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