My wife has a Bersa 9mm thunder compact pro. It has proven to be reliable & accurate I know if I'm not around she can confidently protect herself. As for myself I swap around between carrying a Taurus 1911, Springfield XD 45 Tactical, & a FNS .40.
I have my M&P 9 in my nightstand drawer, which is my open carry weapon. We also have a Glock 19 staged where we can get it fast if not in bed. I have both in holtster w a spare mag so ammo count shouldn't be a issue. I have three Critical Defense rounds followed by alternating FMJ and Critical Defense in case I need to fire trough a barrier. I do plan to replace my 9mm w a fullsize .45 w at least a 5in barrel and minimum of 12 rounds when my cashflow permits.