If I don't plan on using the gun I keep the mags unloaded. All my home defense guns are wheel guns. My carry gun is the only one that usually stays loaded. and I swap them out from time to time. I do this to keep the spring from fatiguing. Back to your question at hand I believe (if i am wrong someone correct me) that the springs will wear out if left loaded all the time.
"I know what you're thinking. "Did he fire six shots or only five?" Well, to tell you the truth, in all this excitement I kind of lost track myself. But being as this is a .44 Magnum, the most powerful handgun in the world, and would blow your head clean off!" - Dirty Harry