If it's your first pistol, shoot hundreds of rounds and become proficient shooting it and with its manual of arms. Then shoot it a bunch more until it feels like it's a part of you.
Then you'll know any quirks or weaknesses and your own preferences as well. That's when to think about any changes you may want to make.
“If ye love wealth better than liberty, the tranquility of servitude better than the animating contest of freedom, go home from us in peace. We ask not your counsels or arms. Crouch down and lick the hands which feed you. May your chains set lightly upon you, and may posterity forget that ye were our countrymen.” ― Samuel Adams