It sounds as if you want a metal framed gun, but what caliber do you prefer? If you want a 45acp, CZ's model 97 (double stack) will be a monster sized grip. I get the impression that won't suffice.
From what I'm hearing, you should primarily focus on a 1911 if you want a 45acp. A Sig P220 is the other reasonable option.
If you want a 9mm/40sw, consider CZ 75 models, Browning Hi-Power, Sig P228/229, or the very slim Sig P239.