The .45 Colt is my favorite. In factory velocity loadings it is extremely mild shooting and very accurate. But handloaded it can be just about anything you want it to be. While the .44 Magnun shines with the light to medium weight bullets, the .45 is outstanding with very heavy bullet weights. These loads are for use in the Ruger frames only, or larger and stouter built guns.
Here a sampling of my .45s:
In the smaller framed guns, such as the Colt and Ubertis, the .45 is even more pleasant shooting, with factory grade, or Cowboy Action loads, than the 22 R.F.