A friend of our family is a successful Surgeon with a health gun collection. He once told me that if he could only have one revolver, it would be his Judge. He didn't put much faith in the effectiveness of any of the .410 cartridges, but he said it was extremely accurate with .45 colt loads, and the ability to use .410 was just icing on the cake.
And that does actually surprise me a bit given the long travel before the bullet actually hits the rifling. But, I don't think he was lying to me, lol.