The Ruger Mark I, II, or III along with the Browning Buckmarks are very accurate and reliable guns. I have read nothing but poor reviews on the Mosquito and to tell you the truth, I have never heard anything good about any 22 auto pistol that resembles that platform, not to say there isn't one out there somewhere but the Rugers and Brownings have their reputation for a reason, most folks who want a semi auto 22 are going to go with one of these 2 makes because they are proven. I don't have any experience with the SR22, Ruger is known to be a good manufacturer but I don't really see the point to that particular gun, it looks more like a small cc type gun and I don't see the point in carrying a 22. For a hunting/range gun to have fun with I'd stick with one of the Marks or Buckmarks or 22/45s. My opinion is they'd be a much more accurate and enjoyable gun, but then I value function over looks. However I'm sure the SR22 is a decent gun if that's what you're into.
Vote Scott Walker for Governor June 5th 2012