If they are factory, get the lot # and contact the manufacturer (you may get a free box for your trouble).
If they are reloads, the primers may have been contaminated.
If the reloads are from someone else (something I don't advise), chalk it up as lesson learned.
"A well regulated Militia, being necessary to the security of a free State, the right of the people to keep and bear Arms, shall not be infringed."
Life Member NRA
Life Member NAHC
Former President of the ECPT (Eifel Combat Pistol Team)