I always found it very important, that the holster in comfortable in all areas.
If you sit a lot, you don`t want the firearm being pushed up from the seat or the grip pushed into the weist.
There are several ways of CCW.
I myself, when I carried my duty gun, preferred a classic pancacke or belt side holster. These had the advanteage of being variable in the position you carry it in.
I also had a Safari Land inside the pants holster, but always found it uncomfortable, since it is being pushed into your weist by your belt, at least the one I had.
My alltime favorite always was a Galco quick draw pancake leather holter.
It was slim and concealed very well but was also variable in it positioning.