mmm. old. bad eyesight. less dexterity. May need to fire one handed and/or possibly beat down an intruder with it. I'll go with my 6" gp100. 357 mag. Heavy enough for defense when empty. Accurate and stable enough for bad eyes. Simple enough for shoddy reflexes.
I hace custom Crimson Trace Lasergrips for every single pisol I own they make them for. I'm trying their new GREEN laser on my newest 1911 long slide 10mm (all the old one's use a red laser). I have fiber optic front sights on my Dan Wesson pistol pack. (1 for EACH of the four barrels in the pack!)
I'd hafta keep my 1972 Colt Python 6", I guess everything else could go, but its a hard decision between my Wiley Clapp GP100 and the Python....more memories and rounds down range with the Python. I literally could hold that baby in my hands foever. It gives me as much satisfaction looking at it as it does shooting it.