Interesting question... I was thinking about it a while. If there was a raging tsunami about to wipe away my house and on end of the room was my pistol and on the other end was my knife and I could only rescue one before the wave hit, I think I'd grab my knife. My dad gave me my first pocket knife at 6, but I didn't shoot a real firearm (outside of BB guns) until I was almost 12. Forty years later and I'm still a lot more confident with a knife than with a pistol. I can use a knife right or left-handed but with pistols I am much more practiced using the right hand. It's funny too.. I won't name a particular knife because I'm comfortable with almost every knife I own
If I did have to choose a single pistol though, it would be the Glock 17 or Glock 19, only because that's what I practice with most often.
(Oh.. I'm big on the 10,000 hour rule. It's the idea that to be masterly proficient at any skill, you need to put in at least 10,000 hours of practice. I'm there with the knife, but not even a fifth of the way there with the pistol. One day I'd like to reach a point where the actual pistol doesn't matter to how well I shoot.)