I assume you mean a standard .45 caliber pistol and not some custom rig.
Having said that, I am sure SOMEONE can do it, a time or two. I highly doubt there is a group of people all working for the government, of all places, that do it regularly.
I do believe someone is pulling your leg a bit...
No. I am pretty sure I can't do it without a TON of practice and a lot of luck.