I hope yours will not be a permanent disability to shoot two-handed.
By off-hand, if you mean shooting one handed, it is a skill all shooters should practice regularly. In a tactical situation your support hand may become disabled, or otherwise occupied and one handed shooting is something useful to know.
By off-hand, if you mean shooting one handed with your usual support hand, ditto the above comment.
To achieve any sort of shooting skill, one or two handed, grip, sight alignment, trigger control and practice, practice, practice.
Cogito, ergo armatum sum
NRA Life Member / SAF Member
Retired Police Detective '71-'01 / LEOSA Certified
Naval Aviation Veteran '65-'69
United States Constitution (c) 1791
All Rights Reserved